Coenzyme Q10 (CoQ10) is a natural anti-oxidant compound whose main function is to produce energy. It is considered a potentially effective factor for the prevention of heart failure, as well as for the protection of patients suffering from cardiovascular diseases in addition to conventional treatment. Some more benefits are: -Olive leaf extract, rich in antioxidant and anti-inflammatory oleuropein, exerts cardioprotective and hypoglycemic action. -It also exerts anti-hypertensive action reducing blood pressure, as well as LDL-cholesterol and triglycerides with a parallel reduction in coronary heart disease risk. -Vitamin Β9 (folic acid) is essential to the development of the nervous system, while it is a potential agent for the treatment of endothelial dysfunction decreasing the risk of cardiovascular diseases. -It contributes to the metabolism of amino acids and is essential for the metabolism of homocysteine, preventing an increase in its levels in the blood and reducing the risk of cardiovascular diseases. -Vitamin B12 (cyanocobalamin) is vital for the normal function of the nervous system, the formation of red blood cells and for DNa synthesis, while its deficiency causes neurological and hematological effects and can affect mood. -Vitamin E (α-Tocopherol) with anti-oxidant and anti-inflammatory action has a protective effect against the onset or complications of the development of cardiovascular diseases, such as heart failure, myocardial infarction and atherosclerosis. -This vitamin is considered to have a neuroprotective effect on brain health and protection against the development of Alzheimer’s disease. -Due to its ability to affect the oxidation of polyunsaturated fatty acids preventing cellular oxidative damage, it is considered to modulate immune functions. -Selenium is an essential trace element providing anti-oxidant and immune functions and reducing oxidative stress and inflammation. -L-carnitine plays an important role in lipid metabolism and in energy production, while it seems to have a protective effect against cardiac disorders. -L-Arginine is a potentially effective therapeutic agent in the treatment of heart failure.