Choline is an important nutrient for the synthesis of neurotransmitters and phospholipids, while its low concentration could possibly cause damage to the liver and muscles and lead to reduced cognitive function. Some more benefits are: -Inositol contributes to the synthesis of structural lipids, messenger compounds and metabolites, important in the physiological functions of the body. -Selenium is an essential trace element providing anti-oxidant and immune functions, reducing oxidative stress and inflammation, and improving mood. -A-lipoic acid (ALA) is an anti-oxidant compound involved in glucose and lipid metabolism and in energy production. -Milk thistle (Silybum marianum) is a herb rich in flavonolignans, which are natural phenols well known as silymarin with anti-inflammatory and immune-modulatory action. -Dandelion (Taraxacum officinale) is a herb widely used for the relief of the symptoms of liver and spleen diseases. -Except for dandelion’s anti-oxidant, anti-inflammatory and analgesic action, it is considered to be a potential diuretic agent. -Moreover, it contributes to the protection of the gastrointestinal tract, improving the clinical symptoms and the inflammatory response of intestinal diseases (such as colitis). -Artichoke (Cynara scolymus) extract improves intestinal transit, enhances intestinal health, contributes to the decrease of cholesterol, enhances the lipids metabolism with parallel reduction of triglycerides, contributes to the glycemic control with hypoglycemic action, has hepatoprotective effects and improves liver’s metabolism. -Boldo (Peumus boldus) extract is mainly used for the relief of dyspepsia symptoms and the treatment of mild gastrointestinal disorders. -Boldine, an alkaloid compound abundant in boldo, ameliorates endothelial dysfunction and the effects of oxidative stress.