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MSM Cream
Size (1)*: 100ml clear please select size
1 2 3 4 5
MSM Cream
Size (1)*: 100ml clear please select size

MSM cream for normal cartilage and joint function, it reduces pain, inflammation, edema and stiffness of the joints.



What it offers

  • Contributes to normal collagen formation

  • Contributes to normal cartilage function

  • Improves joint function

  • Reduces pain

  • Reduces inflammation

  • Reduces edema

  • Reduces stiffness and improves mobility


Why we formulated it
The MSM cream has MSM as its main ingredient, which is an organic form of sulfur and a powerful antioxidant. The primary mechanism of action of MSM is donation of sulfur, which is one of the main components of connective tissue. It has been observed than an inflamed cartilage has one third the concentration level of a healthy cartilage. Additionally, MSM blocks the inflammatory process and boosts the cortisone action. MSM works with elastin fibers, a protein found on the skin tissue, to promote skin elasticity. Harpagophytum (Devil’s Claw) contains harpagoside and B-sitosterol, substances that help reduce pain caused by arthritis as well as improve mobility and flexibility of the joints. Ginger acts as a cyclooxygenase (COX) and lipoxygenase (LOX) inhibitor, in order to inhibit leukotriene synthesis and consequently reduce edema. Arnica contains sesquiterpene lactones, which are known to reduce swelling and relieve pain. Equisetum has a high concentration of sulfur, calcium and many other minerals and protects the joints by promoting collagen production. Nettle leaf extract has anti-inflammatory action and contains a variety of active compounds such as cyclooxygenase (COX) and lipoxygenase (LOX) inhibitors as well as compounds that affect cytokine secretion. Chondroitin  along with Glucosamine contain sulfur, which in combination with collagen produces a fibrous protein that gives the cartilage its structure and flexibility. Hyaluronic acid is a hydrophilic compound with the ability to absorb many water molecules, thus maintaining the natural joint lubrication. Peanut oil reduces inflammation in the suffering area and acts protectively for the skin, keeping it healthy and moisturized.



How to use
Gently massage a sufficient amount onto the problematic area until fully absorbed. You can use the cream 2-3 times a day for as long as you feel it is necessary.


The Physis Laboratory MSM cream is 100% natural and suitable for vegetarians and vegans. It does not contain preservatives or other chemical additives and is not tested on animals.



For external use only

Do not use in children
In case of irritation discontinue use
Do not use on irritated skin with open wounds
Do not use during pregnancy or while breastfeeding


Store in a cool place away from direct sunlight.


Do not use after the expiration date printed on the packaging.



Formulated with

Aqua, Dimethyl sulfone, Glycerin, Cetyl esters, Sodium chondroitin sulfate, Isopropyl isostearate, Ethylhexyl stearate, Dicaprylyl carbonate, Arachidyl alcohol, Triheptanoin, Glyceryl stearate, Cyclopentasiloxane, Glucosamine hydrochloride, Squalane, Behenyl alcohol, Sodium levulinate, Cyclohexasiloxane, Peg–100 stearate, Glyceryl stearate citrate, Arachidyl glucoside, Sodium anisate, Tocopheryl acetate, Dimethicone, Sodium polyacrylate, Harpagophytum procumbens root extract, Zingiber officinale root extract, Arnica montana flower extract, Equisetum arvense leaf extract, Urtica dioica plant extract, Xanthan gum, Hydrogenated polydecene, Citric acid, Sodium gluconate, Sodium sulfite, Trideceth–6, Potassium sorbate, Sodium benzoate, Sodium hyaluronate, Glucose, Parfum, Limonene, Citral, Linalool, Evernia furfuracea extract


Formulated WITHOUT
Preservatives, Chemical additives, Artificial dyes, Fragrance, Genetically Modified Organisms (GMO), Mineral oil



  1. Kim, L. S., et al. "Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial." Osteoarthritis and Cartilage 14.3 (2006): 286-294.

  2. Leblan, D., P. Chantre, and B. Fournie. "Harpagophytum procumbens in the treatment of knee and hip osteoarthritis. Four-month results of a prospective, multicenter, double-blind trial versus diacerhein." Joint, bone, spine: revue du rhumatisme 67.5 (2000): 462-467.

  3. Altman, Roy D., and K. C. Marcussen. "Effects of a ginger extract on knee pain in patients with osteoarthritis." Arthritis & Rheumatism 44.11 (2001): 2531-2538.

  4. Knuesel, Otto, Michel Weber, and Andy Suter. "Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial." Advances in therapy 19.5 (2002): 209.

  5. Farinon, Mirian, et al. "Effect of aqueous extract of giant horsetail (Equisetum giganteum L.) in antigen-induced arthritis." The open rheumatology journal 7 (2013): 129.

  6. Johnson, Tyler A., et al. "Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders." Phytomedicine 20.2 (2013): 143-147.

  7. Riehemann, Kristina, Bert Behnke, and Klaus Schulze-Osthoff. "Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF‐κB." FEBS letters 442.1 (1999): 89-94.

  8. Vassiliou, Evros K., et al. "Oleic acid and peanut oil high in oleic acid reverse the inhibitory effect of insulin production of the inflammatory cytokine TNF-α both in vitro and in vivo systems." Lipids in Health and Disease 8.1 (2009): 25.


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