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Happy Go Liver
€19.50
Size (1)*: 30 κάψουλες clear please select size
1 2
Happy Go Liver
€19.50
Size (1)*: 30 κάψουλες clear please select size

Happy Go Liver is a food supplement that consists of Selenium, Inositol, Choline, Alpha lipoic acid and herbal extracts of Milk thistle, Dandelion, Artichoke, Boldo and Pine. Choline contributes to the synthesis of cellular components, while Inositol participates in basic biological processes of the human body. Selenium helps protect cells from oxidative stress. Milk thistle, Dandelion and Boldo extracts contribute to the normal functioning of the liver. In addition, Dandelion and Artichoke extracts contribute to the normal functioning of the gastrointestinal tract and to normal digestion.

Details

 

What it offers

  • Enhancement of liver function
  • Enhancing the health of the gastrointestinal tract
  • Anti-oxidant properties

 

Why we formulated it

Choline is an important nutrient for the synthesis of neurotransmitters, phospholipids and other necessary cell components, while its low concertation in human body could possibly cause damage of liver, muscles and reduced cognitive function. Another important compound is inositol, which takes part in basic biological processes contributing to the synthesis of structural lipids and other secondary messenger compounds and metabolites, that play important role in the physiological functions of the body. Selenium is an essential trace element providing anti-oxidant and immune functions and reducing oxidative stress and inflammation. Moreover, there are evidences that selenium improves mood. Another anti-oxidant compound is the α-lipoic acid or as well-known ALA, which has several functions such as its involvement in glucose and lipid metabolism and in energy production. Milk thistle (Silybum marianum) is a herb rich in flavonolignans, that are natural phenols well known as silymarin. Silymarin has anti-inflammatory and immune-modulatory action with hepatoprotective effects.  Dandelion (Taraxacum officinale) is a herb with a long history as a medical plant due to the bioactive compounds of its extract and mainly due to its use for the relief of the symptoms of liver and spleen diseases. Except dandelion’s anti-oxidant, anti-inflammatory and analgetic action, it is considered to have several biological activities, while it is considered to be a potential diuretic agent. Moreover, it contributes to the protection of the gastrointestinal tract, improving the clinical symptoms and the inflammatory response of intestinal diseases (such as colitis). Artichoke (Cynara scolymus) is a well-known plant in the Mediterranean region, with the extract of its leaves to be a really promising medical agent, because it improves the intestinal transit, enhances the intestinal health, contributes to the decrease of cholesterol, enhances the lipids metabolism with parallel reduction of triglycerides, contributes to the glycemic control with hypoglycemic action, it has hepatoprotective effects, while it improves liver’s metabolism. Boldo (Peumus boldus) is a native tree of Chile and its extract is a traditional herbal medicinal product mainly used for the relief of dyspepsia symptoms and the treatment of mild gastrointestinal disorders. Boldine is an alkaloid compound, which is abundant in Boldo. Boldine ameliorates the endothelial dysfunction and the effects of the oxidative stress and as a result it is considered to be a good potential therapeutic agent for the treatment of chronic diseases.

Usage

 

Usage
Consume 1-2 capsules per day with water or juice.

Precautions

 

Caution
Not recommended for pregnant women and children under the age of 12. Avoid use in case of kidney or heart failure and/or diabetes.

Do not use in the event of hypersensitivity to any of the ingredients.

Do not exceed the recommended daily dose.

Food supplements should not be used as a substitute for a balanced diet.

Keep out of reach of children.

This product is not intended for the prevention, treatment or cure of human disease. Consult your doctor if you are pregnant, breastfeeding, undergoing pharmaceutical treatment or experiencing health problems.

 

Storage
Store the product in a cool and dry place, away from sources of heat and protected from light.

 

Lifespan
Do not use after the expiration date printed on the packaging. The expiry date stated on the product refers to intact packaging, kept under proper storage conditions.

Ingredients

 

NUTRIENT COMPOSITION

Per daily dose

(1 - 2 capsules)

% RDA*

Milk Thistle extract (Silybum marianum),

 - which provides silymarin

120 - 240 mg

96 – 192 mg

 

Choline (as Choline chloride)

84 - 168 mg

 

Dandelion extract (Taraxacum officinale)

70 – 140 mg

 

Artichoke extract (Cynara scolymus),

 - which provides Cynarin

60 – 120 mg

1,5 – 3 mg

 

Alpha lipoic acid

60 – 120 mg

 

Boldo extract (Peumus boldus Molina),

 - which provides Boldine

40 – 80 mg

20 – 40 μg

 

Pine extract (Pinus sylvestris),

 - which provides Proanthocyanidin

15 – 30 mg

14,25 – 28,5 mg

 

Inositol

10 - 20 mg

 

Selenium (as Selenomethionine)

50 – 100 μg

90,9 – 181,8 %

 

Formulated with
Milk Thistle extract (Silybum marianum), Choline (as Choline chloride), Dandelion extract (Taraxacum officinale), Artichoke extract (Cynara scolymus), Alpha lipoic acid, Boldo extract (Peumus boldus Molina), Pine extract (Pinus sylvestris), Inositol, Selenium (as Selenomethionine), Hydroxypropylmethylcellulose, Magnesium stearate.

 


Formulated WITHOUT
Preservatives, Gluten, Fragrances, Sweeteners, Pigments

 

EOF Notification number
Not. Num. EOF: 106133/19-10-2020
The product is not subject to authorization.

 

Bibliography

 

  1. Ueland, P.M. (2009). Choline and betaine in health and disease. Journal of Inherited Metabolic Disease, 34 (1): 3-15. https://doi.org/10.1007/s10545-010-9088-4
  2. Zeisel, S.H., & da Costa, K.A. (2009). Choline: an essential nutrient for public health. Nutrition Reviews, 67 (11): 615-623. https://dx.doi.org/10.1111%2Fj.1753-4887.2009.00246.x
  3. Bizzarri, M., Fuso, A., Dinicola, S., Cucina, A., & Bevilacqua, A. (2016). Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease. Expert Opinion on Drug Metabolism & Toxicology, 12 (10): 1181-96. https://doi.org/10.1080/17425255.2016.1206887
  4. Ju, W., Li, X., Li, Z., Wu, G.R., Fu, X.F., Yang, X.M., Zhang, X.Q., & Gao, X.B. (2017). The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials. Journal of Trace Elements in Medicine and Biology, 44: 8-16. https://doi.org/10.1016/j.jtemb.2017.04.009
  5. Rayman, M.P. (2000). The importance of selenium to human health. Lancet, 356 (9225): 233-41. https://doi.org/10.1016/S0140-6736(00)02490-9
  6. Salehi, B., Berkay Yılmaz, Y., Antika, G., Boyunegmez Tumer, T., Fawzi Mahomoodally, M., Lobine, D., Akram, M., Riaz, M., Capanoglu, E., Sharopov, F., Martins, N., Cho, W.C., & Sharifi-Rad, J. (2019). Insights on the Use of α-Lipoic Acid for Therapeutic Purposes. Biomolecules, 9 (8), 356. https://doi.org/10.3390/biom9080356
  7. Abenavoli, L., Izzo, A.A., Milic, N., Cicala, C., Santini, A., & Capasso, R. (2018). Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases. Phytotherapy Research, 32 (11):2202-2213. https://doi.org/10.1002/ptr.6171
  8. Martinez, M., Poirrier, P., Chamy, R., Prüfer, D., Schulze-Gronover, C., Jorquera, L., & Ruiz, G. (2015). Taraxacum officinale and related species-An ethnopharmacological review and its potential as a commercial medicinal plant. Journal of Ethnopharmacology, 169: 244-62. https://doi.org/10.1016/j.jep.2015.03.067
  9. Chen, W., Fan, H., Liang, R., Zhang, R., Zhang, J., & Zhu, J. (2019). Taraxacum officinale extract ameliorates dextran sodium sulphate‐induced colitis by regulating fatty acid degradation and microbial dysbiosis. Journal of Cellular and Molecular Medicine, 23: 8161-8172. https://doi.org/10.1111/jcmm.14686
  10. Ben Salem, M., Affes, H., Ksouda, K., Dhouibi, R., Sahnoun, Z., Hammami, S., & Zeghal, K.M. (2015). Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits. Plant Foods for Human Nutrition, 70 (4): 441-53. https://doi.org/10.1007/s11130-015-0503-8
  11. Santos, H.O., Bueno, A.A., & Mota, J.F. (2018). The effect of artichoke on lipid profile: A review of possible mechanisms of action. Pharmacological Research, 137: 170-178. https://doi.org/10.1016/j.phrs.2018.10.007
  12. Jalili, C., Moradi, S., Babaei, A., Boozari, B., Asbaghi, O., Lazaridi, A.V., Kermani, M.A.H., & Miraghajani, M. (2020). Effects of Cynara scolymus L. on glycemic indices:A systematic review and meta-analysis of randomized clinical trials. Complementary Therapies in Medicine, 52: 102496. https://doi.org/10.1016/j.ctim.2020.102496
  13. Committee on Herbal Medicinal Products (2009). Community herbal monograph on Peumus boldus Molina, Folium. Londres: European Medicines Agency.
  14. Lau, Y.S., Ling, W.C., Murugan, D., & Mustafa, M.R. (2015). Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes. Journal of Cardiovascular Pharmacology, 65 (6): 522-31. https://doi.org/10.1097/fjc.0000000000000185

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